Advanced Design Optimization LLC

Advanced Design Optimization


All our CFD methods and accuracy have been well validated through numerous in-vitro and in-vivo testing for many implantable adult and pediatric VAD blood pumps, industrial pumps, and hydro-turbines, etc. A typical example is the fourth generation (PF4) of PedaiFlow Pediatric Ventricular Assist Device (PVAD), developed and optimized using our CFD/FEA-based design optimization. It is an implantable miniature magnetically-levitated turbo-dynamic pediatric ventricular assist device for infants and toddlers with congenital and acquired heart disease. The PF4 shows exceptional hemodynamic performance and unparalleled biocompatibility as already proven with a serial of in-vitro and in-vivo animal trials.  

Blood Pumps
Green Energy
Optimization Cases
Mesh Generation
Miniature PediaFlow-PF4 VAD Model CFD Model and Results for PediaFlow-PF4
Miniature PedaiFlow (PF4) VAD and its flow validation fixture
CFD model and results of PF4
(Please see Ref [1] )

CFD predictions of head and efficiency characteristics of PF4 agreed remarkably well with the validation experimental data: with slight overprediction of head by <7 mmHg over the entire operational range and a slight overprediction in best efficiency by ~1%. The new optimized PF4 extended the maximum flow rate range of previous PF3 device by more than 100% to over 2.3 liter per minute (LPM) for the same range of operating speeds, and doubled the maximum hydraulic efficiency to ~27%.

CFD Predicted H-Q Results for PediaFlow CFD Predicted Efficiebcy-Flow for PediaFlow-PF4

Comparison of CFD predicted h-Q results with the experimental data for PF4. Also superimposed are the experimental data for PF3.

Comparison of CFD predicted H-Q results with the experimental data for PF4. Also superimposed are the experimental data for PF3.

Turbulence is generally modeled by selecting different turbulence models based on Reynolds number and other flow conditions. In particular, for VAD blood pumps, either k-w turbulence model  or  Sear Stress Transport (SST) turbulence model, which combines the standard k-e turbulence model to account for the bulk flow regime and the k-w model for the flow near wall surfaces, is usually prescribed for the turbulent flow simulations. We can also perform more sophisticated turbulence modeling, such as Large Eddy Simulation (LES), for customers.


For details about the accuracy of our CFD simulations and methods, please download here!

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